AdGuard DNS and TS DNS

Good hello! I have a MacBook along with three iOS devices, all running through AdGuard DNS. The only thing that looked relevant was, at the time, TS did not support AdGuard DNS (beta). I was wondering if that changed, or if I needed to resort to either an 4 or 6 setting, OR set up NextDNS to rout everything through AdaGuard, and then use the Next setting in TS…
Any assistance you can provide would be appreciated